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Despite this enhancement in mitochondrial function, differentiated neurons maintained glycolytic activity, suggesting metabolic flexibility

This suggests that SLC7A11 not only plays a critical role in protein and GSH synthesis through cysteine uptake but also dictates glutamine dependence 61

Principles of ubiquitin and SUMO modifications in DNA repair

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Wang Q, Guan YF, Hancock SE et al (2021) Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth

They were found to have significant HbA1c, and weight reduction compared to placebo in patients with diabetes and obesity respectively