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In vivo and in vitro studies confirmed that PQ induced neurotoxicity and oxidative stress via overproduction of ROS and decrease in GSH and antioxidant enzyme levels (77-79)

doi: 10.1038/s41598-018-26882-8 6 CuiYYangDWangWZhangLLiuHMaSet al

They require clinic visits, they cost more, and they don't offer a meaningful advantage over high-dose oral supplementation when absorption isn't the problem

Because the baby depends on the mother's milk for vitamin B12 supply

Most prenatal vitamins contain between 2.6 to 12 mcg of B12, typically enough to meet daily needs for most individuals [*]

This protocol recommends weekly B12/MIC injections for up to 6-months (or 6 total refills)