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Chien et al., 2017)

Finally, the interaction partners of the proteins that passed the GO annotation filter were obtained and these protein pairs were used to reconstruct the network (Figure 3)

A striking example is the widespread dependence of many cancers on glutamine 223,224 , which is sustained by enhanced glutamine synthesis, recycling via autophagy, and increased uptake from the extracellular milieu 225

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23% of the individuals (n = 5,676) across the four cohorts were identified as extreme agers