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Several additional loci showed directionally consistent effects but did not reach statistical significance in external datasets

Moreover, vitamin E slows down the ROS production ( Cucinotta et al., evaluated a metabolic antioxidant therapy combining ubiquinol Q10, Vitamin E, and B-complex vitamins in 59 individuals (42 males and 17 females) with neurodevelopmental disorders

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Replacement of Lys105 by uncharged residues in K105A/Y resulted in a 6597% decrease of the k cat app values for GSSCys and GSH (Fig

KD is primarily used in the treatment of difficult-to-control (refractory) epilepsy in children (8, 9)
