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The peptide was originally derived from the amino acid analysis of Thymalin, a natural thymus extract that had already demonstrated immune-modulating properties in clinical settings

doi: 10.1128/CMR.15.1.125-144.2002

While I have never used expired b12 vials since a pharmacist told me not to I have used multi-use vials after 28 days when they are supposed to be discarded and unrefrigerated once opened as well
