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It was proposed that catalase deficiency may be responsible for the development of diabetes mellitus in an indirect way [24]

miR-21/BDH2 pathway was found to promote iron accumulation during Tfh cell differentiation, further enhancing Fe2+ -dependent TET enzyme activity and BCL6 gene demethylation [26]

doi: 10.1080/14737175.2019.1581610 31

N-acetylcysteine amide (naca) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation

284 A similar phenomenon has been observed in Gln-dependent clear cell renal carcinoma (RCC), which competitively depletes environmental Gln, causing local Gln depletion and IL-23 release from tumor-infiltrating macrophages, which further activates Treg function to suppress tumor immunity