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Consequently, large-scale prospective studies involving patients with appropriate ALS diagnostic criteria to explicate the association between statin use and ALS are recommended in this regard

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Valproic acid may cause hepatotoxicity and increase plasma ammonia, leading to encephalopathy

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Studies show that at doses of 10,000 16,000 mg/day, some people will have an odd, fishy odor due to the excretion of trimethylamine

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