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Description
Within this process, First-in-Human (FIH) trials represent one of the most important transitions in the development of a new medicine

However, persistent burning, stinging, or increasing irritation suggests the concentration may be too high or your skin needs more time to adjust

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De Feo CJ, Aller SG, Siluvai GS, Blackburn NJ, Unger VM

Topical products also face stability challenges
