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343 Evexomostat (SDX-7320), which irreversibly binds METAP2 and regulates insulin, leptin, and adiponectin downstream, was one of the first drugs developed for cancer patients with metabolic complications

This is where human data, clinically supported doses, come into play

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However, due to its antioxidative, anti-inflammatory, and vasculo-, cardio- and neuroprotective properties CBD can mitigate cardiovascular complications of diabetes (Table 4)

Sandmeier et al