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Carnitine forms a high-energy ester bond with long chain fatty acids by the action of carnitine palmitoyl transferase 1 (CPT-1), located in the inner aspect of the outer mitochondrial membrane, with the formation of acylcarnitines [3]

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Metabolic engineering to improve provision of the precursor metabolites L-lysine and S -adenosyL-methionine (SAM) may increase de novo production of L-carnitine by the E