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doi: 10.3389/fnsys.2015.00090 31 DietrichMOBoberJFerreiraJGTellezLAMineurYSSouzaDOet al

In the same year, Wang et al
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Protein modifications include chain fragmentation, site-specific amino acid modifications, proteolysis susceptibility, changes in the electric charge, and alterations in enzymatic activity

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Users with metabolic syndrome or insulin resistance often see the earliest improvements
