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In macrophages, pneumolysin contributes to LMP by the induction of pore formation

99 However, knockdown of bromodomain-containing protein 4 (BRD4), an essential member of the bromodomain and extra-terminal domain (BET) family and epigenetic reader, markedly reduces H4K8la level, increasing A1 polarization in astrocytes and promoting neuronal death by pro-inflammatory factors such as IL-6, IL-1, and TNF-

Gastroenterology 146 , 789800.e788 (2014)

Data set showing the m.z, the matched compound (Kyoto Encyclopedia of Genes and Genomes id), matched form, mass difference, metabolite name, and Log 2 (FC)

These impending studies should incorporate objective assessments of sleep quality, utilizing polysomnography, concurrently with measurements of gut-derived metabolites, amyloid/tau biomarkers, and cognitive trajectories over time

Congenital hyperinsulinemic hypoglycemia and hyperammonemia due to pathogenic variants in GLUD1