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Poor nutrition, stress, and toxins can reduce its levels

Emerging evidence indicates that specific bile acids (BAs), particularly those modulated by the gut microbiota, can directly impact NK cell activity and survival, potentially contributing to tumor immune evasion

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10.1104/pp.103.033027 40 GromesR.HothornM.LenherrE

Additionally, the varying concentration limits in different countriessome allowing up to 4% prescription strength while others restrict over-the-counter usecreate uncertainty about appropriate use

H.ChiangA.CarrellasM.HurtadoJ.et al (2020)