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Within one-carbon metabolism, serum folate is typically lowest during menses and rises into the luteal phase, while plasma homocysteine is lowest in the luteal phase and higher in the follicular/peri-ovulatory window, consistent with hormonally patterned shifts in methyl-group demand, oxidative stress, and inflammatory signaling across the cycle [143]

The American Academy of Pediatrics considers vitamin B12 to be compatible with breast-feeding

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