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These researchers also showed increased levels of lipid peroxidation product malondialdehyde (MDA) compared to controls, with a significant increase from MCI to AD

This is highlighted by the fact that H 2 O 2 mediated oxidation of Cys, GSH and N -acetylcysteine (NAC) thiolates has approximately same rate constants (20 M 1 s 1 ), whereas at pH 7.4 each compound is distinguished by a different rate constant [77]

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