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ImageJ software was used to determine the gray value of the target protein and -tubulin to obtain the relative gray value of the target protein
To generate DIDO and RBM15 SPOC-deleted cell lines, two gRNAs targeting the flanking region of the SPOC domain (DIDO: 5-GGGTCGTGTCTCCCTCTGGA-3 and 5-CCAAGAATTATATTCGGACG-3
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