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PMCID: PMC2439518

9 , e14825 (2021)

Decades of research in the field confirmed that a striking number of genes associated with familial PD are directly or indirectly involved in the regulation of mitochondrial function, including PINK1, Parkin, DJ-1, leucine-rich repeat kinase 2 (LRRK2), -syn, ubiquitin carboxyl-terminal hydrolase ligase-1 (UCHL-1), nuclear receptor-related 1 (NURR1), vacuolar protein sorting 13 C (VPS13 C), and high-temperature demand protein A2 (HTRA2) [125127]

We know you should be training in a certain way generally, but we don't know if you need more or less volume, more or less intensity and more or fewer days per week

Dallman MF, Akana SF, Cascio CS, Darlington DN, Jacobson L, Levin N

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