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These therapeutic approaches aim to reduce myocardial damage and prevent or delay the progression of DCM by targeting ferroptosis, repairing mitochondrial damage, and counteracting oxidative stress (85, 88, 103, 140)

Nicotinamide (NAM) can also be obtained in the diet from the consumption of NAD and NADP, both of which are hydrolyzed to nicotinamide within the lumen of the small intestines

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Consequently, it has implications for every system, from the heart to the brain

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This is a common concern for patients considering GLP-1 receptor agonists like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro)