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n = 14 mice for vehicle group and n = 15 mice for RSL3, Cisplatin and Cisplatin+RSL3 groups

System Xc is composed of the solute carrier family 7 member 11 (SLC7A11) and the solute carrier family 3 member 2 (SLC3A2)

Child Dev 2010;81:2840

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Erwin WM, Ashman K, O'Donnel P, Inman RD: Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes