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Topical phenylephrine, used in-office for iris dilation, and its prodrugs dipivefrin and apraclonidine have been documented to induce AACG [2] Topical anticholinergic/cycloplegics agents used for pupillary dilation may also lead to AACG [2] [1] Botulinum act at peripheral cholinergic synapses, inhibiting the release of acetylcholine

Relaxin treatment reduces angiotensin II-induced vasoconstriction in pregnancy and protects against endothelial dysfunctiondagger

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A five-day course of treatment with lidocaine has been found to reduce symptoms even after the end of treatment

Advances in Therapy