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NNMT enzyme inhibition biochemical studies have characterised 5-Amino-1MQ as a potent, selective NNMT inhibitor in cell-free and cell-culture assays

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Methods We analyzed the metabolic profile of the skn-1-knockdown worms with nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography-tandem mass spectrometry (LCMS/MS) and obtained distinctive metabolomic profiles compared to WT worms

Really, a wide range of buffers will work just fine here

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