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Acetaminophen-induced oxidative stress results in lipid peroxidation, oxidation of protein thiols, mitochondrial injury, altered calcium homeostasis and DNA damage 43
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Therefore, to reduce the ROS activity, host cells are evolved with three types of SODs such as NiSOD, Fe or MnSOD, and CuZnSOD to control the ROS activity produced by itself
The Pew Charitable Trusts"
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