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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

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Ekblom, B., Goldbarg, A.N

The release pattern can be a burst, sustained, or triggered depending on the strength of the interaction and surface chemistry [228]
Further, a pre-clinical study of metastatic lung cancer reported that TDLNs help control metastases after the primary tumor is removed but are not required for adjuvant immunotherapy efficacy (235)
