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Yang, Y., Wang, X

This pro-inflammatory form of cell death holds implication for combating pathogen infection, inflammatory progression (119), and therefore may also contribute to early prevention of inflammatory cancer transformation

A major extracellular enzyme, GPX3, is also found in the cytoplasm and plasma membranes of the mammalian kidney, epididymis, heart, lung, liver, brain, adipose tissue, mammary gland, and gastrointestinal tract (Nirgude and Choudhary, 2021)

Inhibiting these miRNAs (antagomirs) in murine models rescues GPX4 expression and ameliorates tissue damage [45]

[DOI] [PubMed] 95.Irwin DJ, Lee VMY, Trojanowski JQ
