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This is felt to be due to the detoxification effect of B12 in patients who have methylation issues

Detecting why someone has B12 deficiency, is through a combination of taking the patients history and doing further tests

Gonzlez-Guerra JL, Castilla-Cortazar I, Aguirre GA, Muoz U, Martn-Estal I, vila-Gallego E, Granado M, Puche JE, Garca-Villaln A (2017a) The sole partial insulin-like growth factor (IGF-1) deficiency reduces heart contractibility, angiotensin II sensibility, and alters gene expression of structural and functional cardiac proteins Gonzlez-Guerra JL, Castilla-Cortazar I, Aguirre GA et al (2017b) Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins

Unfortunately, many people are unknowingly deficient

Management of Anemia in Young Livestock

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