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The inhibition of sphingolipid biosynthesis disrupts numerous cell functions and signaling pathways, including apoptosis and mitosis, thus potentially contributing to carcinogenesis through an altered balance of cell death and replication [113]
To test this hypothesis, the consumption of NADPH needs to be accurately tracked and determined
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doi: 10.1186/1751-0147-46-229
KurkowskaWBogaczAJaniszewskaMGabryETiszlerMBellantiFet al
Value of endoscopic ultrasound staging in conjunction with the evaluation of lymphovascular invasion in identifying low-risk esophageal carcinoma
