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This has a strong influence on their reactivity, affecting such properties as their accessibility and protonation state (i.e., p K a )

The SS-31 benefits guide covers the mitochondrial support mechanism in detail, while the broader role of energy-supporting peptides provides additional context

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PLoS One 2015;10:e0138815 10.1371/journal.pone.0138815 [DOI] [PMC free article] [PubMed] [Google Scholar] 30

ROS-induced damage to DNA, proteins, and lipids can directly lead to cell death, but it also promotes microglial activation and the release of pro-inflammatory cytokines, further exacerbating neurodegeneration (Tfilin et al., 2023)
