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For a broader look at what B12 does beyond energy including its role in nerves, methylation, and brain health see our complete vitamin B12 benefits guide

Muolokwu CE, Chaulagain B, Gothwal A et al (2024) Functionalized nanoparticles to deliver nucleic acids to the brain for the treatment of Alzheimers disease

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Reversing tumor immune suppression with intratumoral IL-12: activation of tumor-associated T effector/memory cells, induction of T suppressor apoptosis, and infiltration of CD8+ T effectors

Suppression of NLRP3 inflammasome by oral treatment with sulforaphane alleviates acute gouty inflammation

However, these compounds are widely distributed in nature and often suffer from poor bioavailability, raising questions about the translational relevance of their observed effects in vitro