l-carnitine heart failure What is the role of carnitine (L-carnitine) in the management of failure? Carnitine is a friend in

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upregulation of antioxidant enzymes like catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) glutathione peroxidase (GPx), heme oxygenase, endothelial nitric oxide synthase, and other protective proteins (5)

L-carnitine in food L-carnitine is primarily found in meat products , with beef, lamb and mutton showing the highest concentrations

C2 is a downstream product of mitochondrial beta-oxidation of long-chain fatty acids

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However, in a recent whole exome molecular autopsy in unexplained sudden death in young patients, MVP prevalence (7.8%) was higher than expected in the general population and pathogenic/likely pathogenic variants in cardiomyopathy-and channelopathy-susceptibility genes were over-represented (62)