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Sanford 2015

[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Zhou Y, Liyanage PY, Devadoss D, Rios Guevara LR, Cheng L, Graham RM, Chand HS, Al-Youbi AO, Bashammakh AS, El-Shahawi MS, Leblanc RM

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Overlapping chromatograms (Figure 9) of GSH standards further supports that the optimised method has satisfactory specificity with asymmetry factors of 0.821 (20 M)

found that Ag120 acts as an SLC1A5 inhibitor, blocking the uptake and metabolism of Gln, increasing autophagy and oxidative stress in colon cancer cells, and preventing the cancerous growth of CRC cells (85)

It is important to note, however, that epigenetic therapies generally lack specificity, leading to considerable off-target effects and toxicity