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Desensitization of OR is studied on different signaling pathways including ACase inhibition, activation of MAP kinases, inhibition of voltage-gated calcium channels and activation of GIRK channels

[PubMed: 25485838] 148
Particularly, IRE1 regulates many cell functions, including metabolism, immunity, inflammatory cytokine production, cell differentiation, and apoptosis, through the RIDD mechanism, which induces the degradation of certain mRNAs or miRNAs

J Hematol Oncol 2016;9:1-9
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