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Similarly, Komine et al

doi: 10.1016/j.autrev.2014.01.007 3 SkovJCalissendorffJErikssonDMagnussonPKampeOBensingSet al

However, some people may experience mild side effects such as redness or swelling at the injection site

While generation and application of antibodies are restricted to physiological conditions, aptamers can be generated under varying conditions during their in vitro selection

This could lead to the need to increase doses of some drugs to make them effective or could even result in resistance to the drugs

In terms of future direction of investigation, we can continue to comprehensively evaluate the long-term safety and effectiveness of Rg1 through large-scale, multi-center clinical trials