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TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebo-controlled trial (Basel Thyroid Study)

The large amount doesn't pose a danger because people with pernicious anemia absorb only a small fraction of it
doi: 10.1002/mnfr.200400062

Studies demonstrate that PARx can inhibit tumour growth without off-target toxicity in a lung cancer xenograft model

Think of it as the farm-to-table of supplements
M.IvanovaE.GrechkoA
