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Spiekerkoetter U, Vockley J

70 HP 130 AOD-9604 HGH Fragment 176-191 Lipolytic ALIASES AOD-9604, AOD9604, hGH(176-191), Tyr-hGH(177-191) CLASS Synthetic growth-hormone C-terminal fragment lipolytic candidate FORMULA CHNOS SEQUENCE 16-residue fragment corresponding to hGH(177-191) with N-terminal Tyrosine addition HALF-LIFE Short (minutes) plasma ROUTES Subcutaneous (Phase 2 obesity) Oral (food-supplement contexts in some jurisdictions) MECHANISM OF ACTION Synthetic 15-amino-acid fragment of human growth hormone (residues 176-191)

The NHS symptoms list includes persistent tiredness, tingling or numbness in the hands and feet, mouth ulcers, a sore red tongue and problems with memory or concentration

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That specificity makes the peptide valuable for understanding the basic mechanisms of fat storage and mobilization

The mechanistic logic for combining AOD-9604 with GH secretagogues such as ipamorelin or CJC-1295 is that secretagogues increase endogenous GH pulses, which produce their own downstream lipolytic effects, while AOD-9604 acts directly on fat cells independent of the GH axis