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J Clin Immunol , 2021, 41: 270273 Wallace DC

In the present study, we focus on -OHB mainly because it is one of the most predominant ketone bodies in the ketogenic diet, accounting for 78% of the total number of plasma ketone bodies, and has a wide range of metabolic modulatory functions in both physiologic and pathologic states

This foundational knowledge is essential for identifying superior wild strains and providing genetic blueprints for the second pathway: Synthetic Biology and Precision Strain Engineering

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Additionally, MNAM has a low permeability to the membrane, which is crucial for achieving the desired therapeutic effect of the drug (Neelakantan et al., 2018)