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2024 May;49(5):102489

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However, the bloodbrain barrier (BBB) often prevents drugs intended for CNS diseases from effectively crossing into the brain parenchyma to deliver their therapeutic effects

The growth rate of the rats also limits the use of the boot for long-term experiments (12 and 20 weeks), where only fully loaded tendons were studied due to concerns about prolonged unloading and its potential impact on animal welfare

Note it is a research compound rather than a peptide

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