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Also, in these cells, P4 increases the expression of oligodendrocyte progenitor cell markers such as SOX9, NG2, while also inducing the expression of mature oligodendrocyte markers such as MBP and CNP1 (73), indicating that P4 induces oligodendrocyte maturation and myelination

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Another peculiar sex difference was reported in an Iranian observational study ( n = 3362) where lower dietary riboflavin levels were associated with anxiety and depression in middle-aged men ( n = 1403), and psychological distress in middle-aged women ( n = 1959) 61

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