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doi: 10.1038/ncomms14706 281 ArgilesJMBusquetsSStemmlerBLopez-SorianoFJ
One major factor is oxidative stress
The amount people ended up drinking dropped by about 25% when they were already stoned
Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11
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Thus, oxidative stress may lead to increased neuronal apoptosis, as seen in many studies investigating glutathione peroxidases 1 and 4 (Crack et al., 2001
