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In the past few decades, numerous studies have been published about the potential anticancer role of genistein both in cell cultures as well as animal models (Spagnuolo et al., 2015

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Collectively, these observations point to a potential bidirectional relationship among nuclear envelope defects, circadian misalignment, and the accelerated aging phenotypes observed in progeroid syndromes, highlighting the need for direct studies on circadian system integrity in these conditions