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Semaglutide acts on GLP-1 receptors only , while tirzepatide acts on both GLP-1 and GIP receptors

Rowe, S

Frontiers in Pharmacology , 16 , 1619655

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As shown in Figure 1, the workflow used a generic data acquisition method that combined scans of PI, NL, ER, and EPI with polarity switch so that it can be employed for screening compounds with a variety of structures without prior knowledge of their molecular weights or fragmentation patterns