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5-Amino-1MQ operates at the cellular level, inhibiting NNMT and boosting NAD+ to optimize mitochondrial function and promote fat oxidation

Use different injection sites to prevent any potential interaction at the tissue level

Authors contributions Proposal of concept for review and revision of the manuscript (GYW), and writing of the manuscript (LZH)

Some patients may also experience mild hypotension, though severe cardiovascular instability is rare

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All ELISA kits were procured from Thermofisher Scientific and cytokine levels were determined following the manufacturers protocol (Thermofisher Scientific, Waltham, MA, USA)