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To test this, we used sulfur(VI) fluoride exchange (SuFEx)-based click chemistry transformations, in which an iminosulfur oxydifluoride group reacts with primary and secondary aliphatic amines to completion in DMSOPBS mixtures, forming sulfamides or sulfuramidimidoyl fluorides (Fig

To address the issue of multiple comparisons, we employed one-way ANOVA and comparing the mean of each column with the mean of control column LMNA(WT), or no drug control, therefore, we corrected for multiple comparisons using Dunnetts test

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3.1.2 Relationship between lipid metabolism and ferroptosis PUFAs, particularly those containing bis-allylic hydrogen atoms such as arachidonate (AA) and adrenate (AdA), are highly susceptible to oxidation by ROS, making them central to ferroptosis (81)