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Immunity (1999) 10(5):58594

A large number of combinations of histone modifications allow the histone code to flexibly adjust gene expression, which plays an important role in the regulation of brain neuroplasticity and is also associated with neurodegenerative processes [103]

This is because the body may interpret rapid weight loss as a sign of stress or insufficient nutrition, potentially affecting reproductive functions

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Alkaline conditions are used to disrupt the vitamin B12 from the binding proteins, after which the vitamin B12 is generally converted to cyanocobalamin by potassium cyanide, prior to measurement (Klee, 2000)