intracellular glutathione oxidative stress Mitochondrial in Cellular Redox Homeostasis and Disease Manifestation Glutathione Peroxidase 8 Suppression by

Glyoxalase III (GLXIII) enzymes directly convert methylglyoxal to D-lactate in a single step, without using GSH or any other cofactor

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doi: 10.1016/j.febslet.2008.12.023

Earlier analyses supported this association, reporting a stronger relationship between smoking and PBC (pooled OR: 1.67

This critical review deconstructs this duality by providing an integrated analysis of remediation benefits versus mechanistic hazards

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