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397 TTM also exhibits radiosensitizing and chemosensitizing effects, 398,399 enhancing the efficacy of chemotherapeutic agents like doxorubicin, mitomycin C, fenretinide, 5-fluorouracil, and cisplatin in preclinical models without increasing side effects

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The R-domain region from 904-914 matches the backbone distribution and side-chain positions almost exactly, with several identical rotamer positions (Supplementary Fig

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