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Elucidating the mechanisms and host responses triggered by infection may provide valuable insights into disease progression, especially considering that the re-emergence of poxviruses poses an ongoing public health concern

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This interaction suppressed the ROS-dependent antiviral pathway and facilitated viral replication

Here, its cofactor is oxidized by one molecule of hydrogen peroxide and then regenerated by transferring the bound oxygen to a second molecule of substrate

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Lastly, these new insights on disulfide reductase systems should be considered in the context of human health and physiology