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Lung Cancer 49 : 401412 de Jonge MJ, Punt CJ, Sparreboom A, Planting AS, Peters ME, van De Schraaf J, Jackman A, Smith R, de Mulder PH, Verweij J (2002) Phase I and pharmacologic study of oral ZD9331, a novel nonpolyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors

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This compound has been studied for its potential to support: Integrity of the gut lining Soft tissue recovery including tendons and ligaments Angiogenesis (formation of new blood vessels) Inflammation modulation While much discussion has centered on orthopedic recovery, interest is increasing in its possible role in gut-related conditions , including discomfort linked to medications or mucosal lining damage