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The combination produced significantly better outcomes than either treatment alone in animal osteoarthritis models, with improved cartilage preservation and shorter functional recovery times

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Wahl et al., 2014)

Welsh, M., MacLeod, D

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[12, 13, 14] Although this approach has mainly been used in cancer immunotherapy to activate cytotoxic T lymphocytes (CTLs) against tumor antigens, several immunogenic peptide therapeutics have been developed as well for autoimmune diseases including SLE, [15,16] rheumatoid arthritis, [17,18] type 1 diabetes, [19,20] and multiple sclerosis, [21] with varying success