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PW drafted the statistical design of the study, performed power calculations and was involved in the data analysis and interpretation of results

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Marker groups consisting of SDC2 and SEPT9 were detected in urine sediment of CRC cases with a specificity of 70%, showing promise for non-invasive CRC detection through urine liquid biopsy ( SEPT9 plays a crucial role in cell division, and its hypermethylation process is linked to carcinogenesis and can alter the conformation of gene sequences