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The gradual and sustained weight loss is only proven when using the standard therapeutic doses

This pace is fixed, regardless of how the patient is tolerating each increase

Routine screening tools such as the PHQ9 remain essential for identifying depression, especially in patients managing chronic illnesses like diabetes

GLP-1 drugs primarily support glucose control and weight loss, while SGLT2 inhibitors offer strong heart and kidney protection

GLP-1 medicines in kidney inflammation The glucose lowering, hemodynamic benefits, and antiinflammatory actions of GLP-1 medicines may partly explain their efficacy in people with T2D and chronic kidney disease (CKD)

Endocr Rev 2014;35:9921019.ArticlePubMedPMC 23